3-Methanesulfonyloxymethyl-Pyrrolidine-1-Carboxylic acid Tert butyl ester - Names and Identifiers
3-Methanesulfonyloxymethyl-Pyrrolidine-1-Carboxylic acid Tert butyl ester - Physico-chemical Properties
Molecular Formula | C11H21NO5S
|
Molar Mass | 279.35 |
Density | 1.204g/cm3 |
Boling Point | 404.4°C at 760 mmHg |
Flash Point | 198.4°C |
Vapor Presure | 9.44E-07mmHg at 25°C |
Storage Condition | Room Temprature |
Refractive Index | 1.491 |
3-Methanesulfonyloxymethyl-Pyrrolidine-1-Carboxylic acid Tert butyl ester - Risk and Safety
Risk Codes | 25 - Toxic if swallowed
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Safety Description | 45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
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UN IDs | UN 2811 6.1 / PGIII |
Hazard Class | IRRITANT |
3-Methanesulfonyloxymethyl-Pyrrolidine-1-Carboxylic acid Tert butyl ester - Introduction
1-Boc-3-(methylsulfonyloxymethyl) pyrrolidine (also known as Boc-protected tertiary) is an organic compound with the following properties:
1. Appearance: colorless to light yellow crystal or powder.
2. molecular formula: C12H18N2O4S.
3. Molecular weight: 290.35g/mol.
4. Melting point: about 120-130°C.
5. Solubility: Soluble in some organic solvents, such as dimethylformamide and dichloromethane.
One of the main uses of this compound is as a protecting group (protecting group) in organic chemical synthesis. It can protect the amino group (amino group) reactivity, so that it does not occur in the synthesis process of accidental reaction. The amino group can be liberated by removal of the Boc group when it is desired to selectively carry out other reactions.
A method for preparing 1-Boc-3-(methanesulfonyloxymethyl) pyrrolidine is generally obtained by reacting 3-methanesulfonyloxymethylpyrrolidine with a Boc-compound. The reaction is usually carried out in an appropriate organic solvent at room temperature or under slight heating.
Regarding safety information, 1-Boc-3-(methylsulfonyloxymethyl) pyrrolidine is a chemical, so you need to pay attention to safe operation. It may be irritating to the eyes, skin and respiratory system and should be avoided. Use appropriate personal protective equipment such as gloves and goggles when handling. In addition, it should be operated in a well-ventilated place to avoid inhaling its vapors. In case of accidental contact, rinse immediately with plenty of water and seek medical attention immediately. Detailed safety information and operational guidelines can be found in the safety data sheets (MSDS) of the relevant chemicals.
Last Update:2024-04-10 22:29:15